Searchable abstracts of presentations at key conferences in endocrinology

ea0031p289 | Pituitary | SFEBES2013

Maternal corticosterone regulates amino acid allocation to fetal growth in mice

Vaughan Owen , Sferruzzi-Perri Amanda , Fowden Abigail

Synthetic glucocorticoid administration during pregnancy reduces birth weight and increases disease risk in the offspring. This study investigated whether increasing maternal natural corticosterone levels, by endogenous stress or exogenous administration, alters fetal amino acid supply in the mouse.C57BL6/J dams (n=82) were exposed to daily restraint and subcutaneous saline injection (stress) or given corticosterone (cort, 82±11 &#...